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Fame Burst

Mac ‘n’ Cheese Brisket Sandwiches Recipe

Author

Ava Arnold

Updated on April 03, 2026

Slow-cooker mac ’n’ cheese meets brisket in this hearty meal.

Serving Size:

6

Active Time:

20 min.

Total Time:

2 hrs., 20 min.

Ingredients

  • 3½ cups (2%) reduced-fat milk
  • 1 (12 oz.) can evaporated low-fat milk
  • 1 Tbs. spicy brown mustard
  • 1 tsp. salt
  • ⅛ tsp. cayenne pepper
  • 1 lb. elbow macaroni
  • 1 lb. shredded reduced-fat (2% milk) extra-sharp white Cheddar cheese
  • 8 oz. Queso Blanco Velveeta, cut into ½” chunks
  • 1 (16 oz.) pkg. seasoned and cooked sliced brisket or pulled beef, such as Jack Daniel’s
  • 6 sandwich rolls, split

Instructions

  1. Coat 6-qt. slow cooker with cooking spray. Add milk, evaporated milk, mustard, salt and cayenne. Stir in macaroni, Cheddar cheese and Velveeta. Cover; cook on low 2 hrs., or until macaroni is tender. Stir until blended.
  2. Heat sliced brisket or pulled beef according to package directions; divide meat evenly among roll bottoms. Top each with ¾ cup macaroni and cheese, then roll tops. Transfer remaining macaroni and cheese to bowl. Cover; chill and reserve for another use.
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